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Prof. Peter Nürnberg, Ph.D. Cologne Center for Genomics (CCG) University of Cologne D-50931 Köln/Germany Phone: +221-478-96800 Fax: +221-478-96803 email: nuernberg(at)uni-koeln(dot)de |
Curriculum Vitae
| 1981 | Diploma in Biology, Humboldt-University Berlin |
| 1981-1984 | Ph.D. thesis (Dr. rer. nat.) in Biochemistry, Humboldt-University Berlin |
| 1984-1987 | Post-doc at the Central Institute of Molecular Biology, Berlin-Buch |
| 1987-1989 | Staff member, Institute of Medical Genetics, Charité, Berlin |
| 1990 | Visiting Research Investigator, AG Epplen, Max Planck Institute of Psychiatry, Martinsried/ Bavaria |
| 1990-2000 | Head of the Dept. of Molecular Genetics, Institute of Medical Genetics, Charité, Berlin |
| 1997 | Postdoctoral lecturing qualification (Habilitation) with papers on genomic repetitive elements and their application as markers in molecular genetics, Humboldt-University Berlin |
| 1998-2004 | Appointment to “Oberassistent” (C2) at the Institute of Medical Genetics, Charité, Berlin |
| 2000-2004 | Head of the Gene Mapping Center (GMC) at the Max Delbrück Center (MDC) for Molecular Medicine, Berlin-Buch |
| Since 2004 | Professor (full) of Genomics, University of Cologne, Head of the Cologne Center for Genomics |
Awards and Honors
Humboldt Award 1985
Research Activities
- Projects in CMMC (Centre of Molecular Medicine Cologne)
- SFB577
- SFB680
- collaborative research projects within the NGFN
- Network activities in GeneSkin
- coordinating and core center activities in EPICURE (FP6)
Memberships (Selection)
- Coordinator of the National Genotyping Platform of the NGFN
- President of the "Arbeitsgemeinschaft für Gendiagnostik e.V." (AGD)
- CEO of the Atlas Biolabs GmbH
Selected Publications
Sayer JA, Otto EA, O'toole JF, Nürnberg G, Kennedy MA, Becker C, Hennies HC, Helou J, Attanasio M, Fausett BV, Utsch B, Khanna H, Liu Y, Drummond I, Kawakami I, Kusakabe T, Tsuda M, Ma L, Lee H, Larson RG, Allen SJ, Wilkinson CJ, Nigg EA, Shou C, Lillo C, Williams DS, Hoppe B, Kemper MJ, Neuhaus T, Parisi MA, Glass IA, Petry M, Kispert A, Gloy J, Ganner A, Walz G, Zhu X, Goldman D, Nürnberg P, Swaroop A, Leroux MR, and Hildebrandt F. The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat. Genet. 2006, 38(6): 674-81.
Rohmann E, Brunner HG, Kayserili H, Uyguner O, Nurnberg G, Lew ED, Dobbie A, Eswarakumar VP, Uzumcu A, Ulubil-Emeroglu M, Leroy JG, Li Y, Becker C, Lehnerdt K, Cremers CW, Yuksel-Apak M, Nürnberg P, Kubisch C, Schlessinger J, van Bokhoven H, and Wollnik B. Mutations in different components of FGF signaling in LADD syndrome. Nat. Genet. 2006, 38: 414-7.
Franke A, Wollstein A, Teuber M, Wittig M, Lu T, Hoffmann K, Nürnberg P, Krawczak M, Schreiber S, and Hampe J. GENOMIZER:an integrated analysis system for genome-wide association data. Hum. Mutat. 2006, 27: 583-588.
Gödde R, Rohde K, Becker C, Toliat MR, Entz P, Suk A, Muller N, Sindern E, Haupts M, Schimrigk S, Nürnberg P, and Epplen JT. Association of the HLA region with multiple sclerosis as confirmed by a genome screen using >10,000 SNPs on DNA chips. J. Mol. Med. 2005, 83: 486-494.
Metherell LA, Chapple JP, Cooray S, David A, Becker C, Ruschendorf F, Naville D, Begeot M, Khoo B, Nürnberg P, Huebner A, Cheetham ME, and Clark AJ. Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2. Nat. Genet. 2005, 37: 166-170.
Kulle B, Schirmer M, Toliat MR, Suk A, Becker C, Tzvetkov MV, Brockmoller J, Bickeboller H, Hasenfuss G, Nürnberg P, and Wojnowski L. Application of genomewide SNP arrays for detection of simulated susceptibility loci. Hum. Mutat. 2005, 25: 557-565.
Janecke AR, Thompson DA, Utermann G, Becker C, Hubner CA, Schmid E, McHenry CL, Nair AR, Ruschendorf F, Heckenlively J, Wissinger B, Nürnberg P, and Gal A. Mutations in RDH12 encoding a photoreceptor cell retinol dehydrogenase cause childhood-onsetsevere retinal dystrophy. Nat. Genet. 2004, 36: 850-4.
Knoblauch H, Bauerfeind A, Toliat MR, Becker C, Luganskaja T, Gunther UP, Rohde K, Schuster H, Junghans C, Luft FC, Nürnberg P, and Reich JG. Haplotypes and SNPs in 13 lipid-relevant genes explain most of the genetic variance in high-density lipoprotein and low-density lipoprotein cholesterol. Hum. Mol. Genet. 2004, 13: 993-1004.
Rutsch F, Ruf N, Vaingankar S, Toliat MR, Suk A, Hohne W, Schauer G, Lehmann M, Roscioli T, Schnabel D, Epplen JT, Knisely A, Superti-Furga A, McGill J, Filippone M, Sinaiko AR, Vallance H, Hinrichs B, Smith W, Ferre M, Terkeltaub R, and Nürnberg P. Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification. Nat. Genet. 2003, 34: 379-381.
Nürnberg P, Thiele H, Chandler D, Hohne W, Cunningham ML, Ritter H, Leschik G, Uhlmann K, Mischung C, Harrop K, Goldblatt J, Borochowitz ZU, Kotzot D, Westermann F, Mundlos S, Braun HS, Laing N, and Tinschert S. Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia. Nat. Genet. 2001, 28: 37-41.
