Logo of University of Cologne

Publications - Epilepsy Genetics Group

2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000

1999 and later

 

2015

 

2014

 

Anney, R.J.L., Avbersek, A., Balding, D., Baum, L., Becker, F., Berkovic, S.F., Bradfield, J.P., Brody, L.C., Buono, R.J., Catarino, C.B., Cavalleri, G.L., Cherny, S.S., Chinthapalli, K., Coffey, A.J., Compston, A., Cossette, P., de Haan, G.J., De Jonghe, P., de Kovel, C.G.F., Delanty, N., Depondt, C., Dlugos, D.J., Doherty, C.P., Elger, C.E., Ferraro, T.N., Feucht, M., Franke, A., French, J., Gaus, V., Goldstein, D.B., Gui, H.S., Guo, Y.L., Hakonarson, H., Hallmann, K., Heinzen, E.L., Helbig, I., Hjalgrim, H., Jackson, M., Jamnadas-Khoda, J., Janz, D., Johnson, M.R., Kalviainen, R., Kantanen, A.M., Kasperaviciute, D., Trenite, D.K.N., Koeleman, B.P.C., Kunz, W.S., Kwan, P., Lau, Y.L., Lehesjoki, A.E., Lerche, H., Leu, C., Lieb, W., Lindhout, D., Lo, W., Lowenstein, D.H., Malovini, A., Marson, A.G., McCormack, M., Mills, J.L., Moerzinger, M., Moller, R.S., Molloy, A.M., Muhle, H., Newton, M., Ng, P.W., Nothen, M.M., Nurnberg, P., Obrien, T.J., Oliver, K.L., Palotie, A., Pangilinan, F., Pernhorst, K., Petrovski, S., Privitera, M., Radtke, R., Reif, P.S., Rosenow, F., Ruppert, A.K., Sander, T., Scattergood, T., Schachter, S., Schankin, C., Scheffer, I.E., Schmitz, B., Schoch, S., Sham, P.C., Sisodiya, S., Smith, D.F., Smith, P.E., Speed, D., Sperling, M.R., Steffens, M., Stephani, U., Striano, P., Stroink, H., Surges, R., Tan, K.M., Thomas, G.N., Todaro, M., Tostevin, A., Tozzi, R., Trucks, H., Visscher, F., von Spiczak, S., Walley, N.M., Weber, Y.G., Wei, Z., Whelan, C., Yang, W.L., Zara, F., Zimprich, F., Int League Epilepsy Consortium, C., and Grp, K.S. (2014). Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies. Lancet Neurol 13, 893-903.

Assereto, S., Robbiano, A., Di Rocco, M., Rossi, A., Cassandrini, D., Panicucci, C., Brigati, G., Biancheri, R., Bruno, C., Minetti, C., Trucks, H., Sander, T., Zara, F., and Gazzerro, E. (2014). Functional characterization of the c.462delA mutation in the NDUFS4 subunit gene of mitochondrial complex I. Clin Genet 86, 99-101.

Dejanovic, B., Lal, D., Catarino, C.B., Arjune, S., Belaidi, A.A., Trucks, H., Vollmar, C., Surges, R., Kunz, W.S., Motameny, S., Altmüller, J., Köhler, A., Neubauer, B.A., Epicure, C., Nürnberg, P., Noachtar, S., Schwarz, G., and Sander, T. (2014). Exonic microdeletions of the gephyrin gene impair GABAergic synaptic inhibition in patients with idiopathic generalized epilepsy. Neurobiol Dis 67, 88-96.

Hallmann, K., Zsurka, G., Moskau-Hartmann, S., Kirschner, J., Korinthenberg, R., Ruppert, A.K., Ozdemir, O., Weber, Y., Becker, F., Lerche, H., Elger, C.E., Thiele, H., Nürnberg, P., Sander, T., and Kunz, W.S. (2014). A homozygous splice-site mutation in CARS2 is associated with progressive myoclonic epilepsy. Neurology 83, 2183-2187.

Lal, D., Reinthaler, E.M., Schubert, J., Muhle, H., Riesch, E., Kluger, G., Jabbari, K., Kawalia, A., Bäumel, C., Holthausen, H., Hahn, A., Feucht, M., Neophytou, B., Haberlandt, E., Becker, F., Altmüller, J., Thiele, H., Lemke, J.R., Lerche, H., Nürnberg, P., Sander, T., Weber, Y., Zimprich, F., and Neubauer, B.A. (2014). DEPDC5 mutations in genetic focal epilepsies of childhood. Ann Neurol 75, 788-792.

Menzler, K., Hermsen, A., Balkenhol, K., Duddek, C., Bugiel, H., Bauer, S., Schorge, S., Reif, P.S., Klein, K.M., Haag, A., Oertel, W.H., Hamer, H.M., Knake, S., Trucks, H., Sander, T., Rosenow, F., Consortium, E., Avanzini, G., Baulac, M., Bentivoglio, M., Blumcke, I., Cesuroglu, T., Freund, T., Beck, H., Heinemann, U., Kokaia, M., Koelemann, B., Lehesjoki, A.E., Lerche, H., Luhmann, H., Ozbek, U., Perucca, E., Pitkanen, A., Serratosa, J., Simonato, M., Sperk, G., Walker, M., Vezzani, A., Zara, F., Zelphati, O., Wahlbeg, L.U., Menn, B., Glynn, M., Finocchiaro, C., Guerrini, R., Baker, M., Lund, S., de Boer, H., and Mifsud, J. (2014). A common SCN1A splice-site polymorphism modifies the effect of carbamazepine on cortical excitability--a pharmacogenetic transcranial magnetic stimulation study. Epilepsia 55, 362-369.

Pernhorst, K., van Loo, K.M.J., von Lehe, M., Priebe, L., Cichon, S., Herms, S., Hoffmann, P., Helmstaedter, C., Sander, T., Schoch, S., and Becker, A.J. (2014). Rs6295 promoter variants of the serotonin type 1A receptor are differentially activated by c-Jun in vitro and correlate to transcript levels in human epileptic brain tissue (vol 1499, pg 136, 2013). Brain Res 1555, 97-98.

Reinthaler, E.M., Lal, D., Jurkowski, W., Feucht, M., Steinböck, H., Gruber-Sedlmayr, U., Ronen, G.M., Geldner, J., Haberlandt, E., Neophytou, B., Hahn, A., Altmüller, J., Thiele, H., Toliat, M.R., Euro, E.C., Lerche, H., Nürnberg, P., Sander, T., Neubauer, B.A., and Zimprich, F. (2014). Analysis of ELP4, SRPX2, and interacting genes in typical and atypical rolandic epilepsy. Epilepsia 55, e89-93.

Reinthaler, E.M., Lal, D., Lebon, S., Hildebrand, M.S., Dahl, H.H., Regan, B.M., Feucht, M., Steinböck, H., Neophytou, B., Ronen, G.M., Roche, L., Gruber-Sedlmayr, U., Geldner, J., Haberlandt, E., Hoffmann, P., Herms, S., Gieger, C., Waldenberger, M., Franke, A., Wittig, M., Schoch, S., Becker, A.J., Hahn, A., Männik, K., Toliat, M.R., Winterer, G., p11.2 European, C., Lerche, H., Nürnberg, P., Mefford, H., Scheffer, I.E., Berkovic, S.F., Beckmann, J.S., Consortium, E., Euro, E.C., Sander, T., Jacquemont, S., Reymond, A., Zimprich, F., Neubauer, B.A., Neubauer, B., Mörzinger, M., Suls, A., Weckhuysen, S., Claes, L., Deprez, L., Smets, K., Van Dyck, T., Deconinck, T., De Jonghe, P., Møller, R.S., Klitten, L.L., Hjalgrim, H., Campus, K., Helbig, I., Muhle, H., Ostertag, P., von Spiczak, S., Stephani, U., Trucks, H., Elger, C.E., Kleefuß-Lie, A.A., Kunz, W.S., Surges, R., Gaus, V., Janz, D., Schmitz, B., Rosenow, F., Klein, K.M., Reif, P.S., Oertel, W.H., Hamer, H.M., Becker, F., Weber, Y., Koeleman, B.P., de Kovel, C., Lindhout, D., Ameil, A., Andrieux, J., Bouquillon, S., Boute, O., Cordier, M.P., Cuisset, J.M., Cuvellier, J.C., David, A., de Vries, B., Delrue, M.A., Doco-Fenzy, M., Fernandez, B.A., Heron, D., Keren, B., Lebel, R., Leheup, B., Lewis, S., Mencarelli, M.A., Mignot, C., Minet, J.C., Moerman, A., Morice-Picard, F., Mucciolo, M., Ounap, K., Pasquier, L., Petit, F., Ragona, F., Rajcan-Separovic, E., Renieri, A., Rieubland, C., Sanlaville, D., Sarrazin, E., Shen, Y., van Haelst, M., and Vulto-van Silfhout, A. (2014). 16p11.2 600 kb Duplications confer risk for typical and atypical Rolandic epilepsy. Hum Mol Genet 23, 6069-6080.

Schilling, C., Kühn, S., Sander, T., and Gallinat, J. (2014). Association between dopamine D4 receptor genotype and trait impulsiveness. Psychiatr Genet 24, 82.

Schubert, J., Siekierska, A., Langlois, M., May, P., Huneau, C., Becker, F., Muhle, H., Suls, A., Lemke, J.R., de Kovel, C.G., Thiele, H., Konrad, K., Kawalia, A., Toliat, M.R., Sander, T., Rüschendorf, F., Caliebe, A., Nagel, I., Kohl, B., Kecskés, A., Jacmin, M., Hardies, K., Weckhuysen, S., Riesch, E., Dorn, T., Brilstra, E.H., Baulac, S., Møller, R.S., Hjalgrim, H., Koeleman, B.P., Euro, E.R.E.S.C., Jurkat-Rott, K., Lehman-Horn, F., Roach, J.C., Glusman, G., Hood, L., Galas, D.J., Martin, B., de Witte, P.A., Biskup, S., De Jonghe, P., Helbig, I., Balling, R., Nürnberg, P., Crawford, A.D., Esguerra, C.V., Weber, Y.G., and Lerche, H. (2014). Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes. Nat Genet 46, 1327-1332.

Vanni, N., Fruscione, F., Ferlazzo, E., Striano, P., Robbiano, A., Traverso, M., Sander, T., Falace, A., Gazzerro, E., Bramanti, P., Bielawski, J., Fassio, A., Minetti, C., Genton, P., and Zara, F. (2014). Impairment of ceramide synthesis causes a novel progressive myoclonus epilepsy. Ann Neurol 76, 206-212.

 

2013

Assereto, S., Robbiano, A., Di Rocco, M., Rossi, A., Cassandrini, D., Panicucci, C., Brigati, G., Biancheri, R., Bruno, C., Minetti, C., Trucks, H., Sander, T., Zara, F., and Gazzerro, E. (2013). Functional characterization of the c.462delA mutation in the NDUFS4 subunit gene of mitochondrial complex I. Clin Genet.

Biancheri, R., Cassandrini, D., Pinto, F., Trovato, R., Di Rocco, M., Mirabelli-Badenier, M., Pedemonte, M., Panicucci, C., Trucks, H., Sander, T., Zara, F., Rossi, A., Striano, P., Minetti, C., and Santorelli, F.M. (2013). EXOSC3 mutations in isolated cerebellar hypoplasia and spinal anterior horn involvement. J Neurol 260, 1866-1870.

Fehr, C., Sommerlad, D., Sander, T., Anghelescu, I., Dahmen, N., Szegedi, A., Mueller, C., Zill, P., Soyka, M., and Preuss, U.W. (2013). Association of VMAT2 gene polymorphisms with alcohol dependence. J Neural Transm 120, 1161-1169.

Lal, D., Becker, K., Motameny, S., Altmuller, J., Thiele, H., Nurnberg, P., Ahting, U., Rolinski, B., Neubauer, B.A., and Hahn, A. (2013). Homozygous missense mutation of NDUFV1 as the cause of infantile bilateral striatal necrosis. Neurogenetics 14, 85-87.

Lal, D., Reinthaler, E.M., Altmuller, J., Toliat, M.R., Thiele, H., Nurnberg, P., Lerche, H., Hahn, A., Moller, R.S., Muhle, H., Sander, T., Zimprich, F., and Neubauer, B.A. (2013). RBFOX1 and RBFOX3 Mutations in Rolandic Epilepsy. PLoS ONE 8.

Lal, D., Trucks, H., Moller, R.S., Hjalgrim, H., Koeleman, B.P.C., de Kovel, C.G.F., Visscher, F., Weber, Y.G., Lerche, H., Becker, F., Schankin, C.J., Neubauer, B.A., Surges, R., Kunz, W.S., Zimprich, F., Franke, A., Illig, T., Ried, J.S., Leu, C., Nurnberg, P., Sander, T., Consortium, E., and Consortium, E. (2013). Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy. Epilepsia 54, 265-271.

Lemke, J.R., Lal, D., Reinthaler, E.M., Steiner, I., Nothnagel, M., Alber, M., Geider, K., Laube, B., Schwake, M., Finsterwalder, K., Franke, A., Schilhabel, M., Jahn, J.A., Muhle, H., Boor, R., Van Paesschen, W., Caraballo, R., Fejerman, N., Weckhuysen, S., De Jonghe, P., Larsen, J., Moller, R.S., Hjalgrim, H., Addis, L., Tang, S., Hughes, E., Pal, D.K., Veri, K., Vaher, U., Talvik, T., Dimova, P., Lopez, R.G., Serratosa, J.M., Linnankivi, T., Lehesjoki, A.E., Ruf, S., Wolff, M., Buerki, S., Wohlrab, G., Kroell, J., Datta, A.N., Fiedler, B., Kurlemann, G., Kluger, G., Hahn, A., Haberlandt, D.E., Kutzer, C., Sperner, J., Becker, F., Weber, Y.G., Feucht, M., Steinbock, H., Neophythou, B., Ronen, G.M., Gruber-Sedlmayr, U., Geldner, J., Harvey, R.J., Hoffmann, P., Herms, S., Altmuller, J., Toliat, M.R., Thiele, H., Nurnberg, P., Wilhelm, C., Stephani, U., Helbig, I., Lerche, H., Zimprich, F., Neubauer, B.A., Biskup, S., and von Spiczak, S. (2013). Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes. Nature genetics 45, 1067-+.

Moller, R.S., Weber, Y.G., Klitten, L.L., Trucks, H., Muhle, H., Kunz, W.S., Mefford, H.C., Franke, A., Kautza, M., Wolf, P., Dennig, D., Schreiber, S., Ruckert, I.M., Wichmann, H.E., Ernst, J.P., Schurmann, C., Grabe, H.J., Tommerup, N., Stephani, U., Lerche, H., Hjalgrim, H., Helbig, I., Sander, T., and Consortium, E. (2013). Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy. Epilepsia 54, 256-264.

Mullen, S.A., Carvill, G.L., Bellows, S., Bayly, M.A., Trucks, H., Lal, D., Sander, T., Berkovic, S.F., Dibbens, L.M., Scheffer, I.E., and Mefford, H.C. (2013). Copy number variants are frequent in genetic generalized epilepsy with intellectual disability. Neurology 81, 1507-1514.

Pernhorst, K., Herms, S., Hoffmann, P., Cichon, S., Schulz, H., Sander, T., Schoch, S., Becker, A.J., and Grote, A. (2013). TLR4, ATF-3 and IL8 inflammation mediator expression correlates with seizure frequency in human epileptic brain tissue. Seizure-Eur J Epilep 22, 675-678.

Pernhorst, K., van Loo, K.M.J., von Lehe, M., Priebe, L., Cichon, S., Herm, S., Hoffmann, P., Helmstaedter, C., Sander, T., Schoch, S., and Becker, A.J. (2013). Rs6295 promoter variants of the serotonin type 1A receptor are differentially activated by c-Jun in vitro and correlate to transcript levels in human epileptic brain tissue. Brain research 1499, 136-144.

Schilling, C., Kuhn, S., Sander, T., and Gallinat, J. (2013). Association between dopamine D4 receptor genotype and trait impulsiveness. Psychiatric genetics.

Stolting, G., Teodorescu, G., Begemann, B., Schubert, J., Nabbout, R., Toliat, M.R., Sander, T., Nurnberg, P., Lerche, H., and Fahlke, C. (2013). Regulation of ClC-2 gating by intracellular ATP. Pflug Arch Eur J Phy 465, 1423-1437.

 

2012

EPICURE Consortium, EMINet Consortium, Steffens,M., Leu,C., Ruppert,A.K., Zara,F., Striano,P., Robbiano,A., Capovilla,G., Tinuper,P., Gambardella,A., Bianchi,A., La Neve,A., Crichiutti,G., de Kovel,C.G., Kasteleijn-Nolst Trenité,D., de Haan,G.J., Lindhout,D., Gaus,V., Schmitz,B., Janz,D., Weber,Y.G., Becker,F., Lerche,H., Steinhoff,B.J., Kleefuß-Lie,A.A., Kunz,W.S., Surges,R., Elger,C.E., Muhle,H., von Spiczak,S., Ostertag,P., Helbig,I., Stephani,U., Møller,R.S., Hjalgrim,H., Dibbens,L.M., Bellows,S., Oliver,K., Mullen,S., Scheffer,I.E., Berkovic,S.F., Everett,K.V., Gardiner,M.R., Marini,C., Guerrini,R., Lehesjoki,A.E., Siren,A., Guipponi,M., Malafosse,A., Thomas,P., Nabbout,R., Baulac,S., Leguern,E., Guerrero,R., Serratosa,J.M., Reif,P.S., Rosenow,F., Mörzinger,M., Feucht,M., Zimprich,F., Kapser,C., Schankin,C.J., Suls,A., Smets,K., De Jonghe,P., Jordanova,A., Caglayan,H., Yapici,Z., Yalcin,D.A., Baykan,B., Bebek,N., Ozbek,U., Gieger,C., Wichmann,H.E., Balschun,T., Ellinghaus,D., Franke,A., Meesters,C., Becker,T., Wienker,T.F., Hempelmann,A., Schulz,H., Rüschendorf,F., Leber,M., Pauck,S.M., Trucks,H., Toliat,M.R., Nürnberg,P., Avanzini,G., Koeleman,B.P., and Sander,T. (2012). Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32. Hum Mol Genet. 21, 5359-5372.

EPICURE Consortium, Leu,C., de Kovel,C.G., Zara,F., Striano,P., Pezzella,M., Robbiano,A., Bianchi,A., Bisulli,F., Coppola,A., Giallonardo,A.T., Beccaria,F., Trenité,D.K., Lindhout,D., Gaus,V., Schmitz,B., Janz,D., Weber,Y.G., Becker,F., Lerche,H., Kleefuss-Lie,A.A., Hallman,K., Kunz,W.S., Elger,C.E., Muhle,H., Stephani,U., Møller,R.S., Hjalgrim,H., Mullen,S., Scheffer,I.E., Berkovic,S.F., Everett,K.V., Gardiner,M.R., Marini,C., Guerrini,R., Lehesjoki,A.E., Siren,A., Nabbout,R., Baulac,S., Leguern,E., Serratosa,J.M., Rosenow,F., Feucht,M., Unterberger,I., Covanis,A., Suls,A., Weckhuysen,S., Kaneva,R., Caglayan,H., Turkdogan,D., Baykan,B., Bebek,N., Ozbek,U., Hempelmann,A., Schulz,H., Rüschendorf,F., Trucks,H., Nürnberg,P., Avanzini,G., Koeleman,B.P., Sander,T., Zimprich,F., Mçrzinger,M., Feucht,M., Suls,A., Weckhuysen,S., Claes,L., Deprez,L., Smets,K., Van Dyck,T., Deconinck,T., De Jonghe,P., Velizarova,R., Dimova,P., Radionova,M., Tournev,I., Kancheva,D., Kaneva,R., Jordanova,A., Møller,R.S., Hjalgrim,H., Møller,R.S., Lehesjoki,A.E., Siren,A., Baulac,M., Baulac,S., Gourfinkel-An,I., Helbig,I., Muhle,H., von Spiczak,S., Ostertag,P., Stephani,U., Leber,M., Leu,C., Sander,T., Toliat,M.R., Trucks,H., Nürnberg,P., Hempelmann,A., Rüschendorf,F., Sander,T., Elger,C.E., Hallmann,K., Kleefuss-Lie,A.A., Kunz,W.S., Gaus,V., Janz,D., Sander,T., Schmitz,B., Klein,K.M., Reif,P.S., Oertel,W.H., Hamer,H.M., Rosenow,F., Becker,F., Weber,Y., Lerche,H., Marini,C., Guerrini,R., Mei,D., Norci,V., Zara,F., Striano,P., Robbiano,A., Pezzella,M., Bianchi,A., Gambardella,A., Tinuper,P., La Neve,A., Capovilla,G., Vigliano,P., Crichiutti,G., Vanadia,F., Vignoli,A., Coppola,A., Striano,S., Egeo,G., Giallonardo,A.T., Franceschetti,S., Belcastro,V., Benna,P., Coppola,G., De Palo,A., Ferlazzo,E., Vecchi,M., Martinelli,V., Bisulli,F., Beccaria,F., Del Giudice,E., Mancardi,M., Stranci,G., Scabar,A., Gobbi,G., Giordano,I., Guerero,R., Giraldez,B.G., Serratosa,J.M., Koeleman,B.P., de Kovel,C., Lindhout,D., de Haan,G.J., Ozbek,U., Bebek,N., Baykan,B., Ozdemir,O., Ugur,S., Kocasoy-Orhan,E., Yücesan,E., Cine,N., Gokyigit,A., Gurses,C., Gul,G., Ayta,S., Yapici,Z., Ozkara,C., Caglayan,H., Yalcin,O., Yalcin,D., Turkdogan,D., Arslan,K., Bozdemir,H., Dizdarer,G., and Uluduz,D. (2012). Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies. Epilepsia. 53, 308-318.

Hermsen,A., Menzler,K., Reif,P.S., Balkenhol,K., Bugiel,H., Klein,K.M., Duddek,C., Hamer,H.M., Trucks,H., Sander,T., Haag,A., and Rosenow,F. (2012). THE SCN1A-PLOYMORPHISM AND CARBAMAZEPINE - EFFECTS ON CORTICAL EXCITABILITY IN HEALTHY ADULTS IN A TMS-STUDY IN THE EPICURE-CONSORTIUM. Epilepsia. 53 5, 133.

Striano,P., Weber,Y.G., Toliat,M.R., Schubert,J., Leu,C., Chaimana,R., Baulac,S., Guerrero,R., Leguern,E., Lehesjoki,A.E., Polvi,A., Robbiano,A., Serratosa,J.M., Guerrini,R., Nürnberg,P., Sander,T., Zara,F., Lerche,H., Marini,C., and EPICURE Consortium (2012). GLUT1 mutations are a rare cause of familial idiopathic generalized epilepsy. Neurology. 78, 557-562.

Wirth,C., Schubert,F., Lautenschlager,M., Brühl,R., Klär,A., Majic,T., Lang,U.E., Ehrlich,A., Winterer,G., Sander,T., Schouler-Ocak,M., and Gallinat,J. (2012). DTNBP1 (dysbindin) gene variants: in vivo evidence for effects on hippocampal glutamate status. Curr Pharm Biotechnol. 13, 1513-1521.

 

2011

Giegling,I., Drago,A., Schafer,M., Hartmann,A.M., Sander,T., Toliat,M.R., Moller,H.J., De Ronchi,D., Stassen,H.H., Rujescu,D., and Serretti,A. (2011). Lack of association between 71 variations located in candidate genes and response to acute haloperidol treatment. Psychopharmacology 214, 719-728.

Giegling,I., Drago,A., Dolzan,V., Plesnicar,B.K., Schafer,M., Hartmann,A.M., Sander,T., Toliat,M.R., Moller,H.J., Stassen,H.H., Rujescu,D., and Serretti,A. (2011). Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol. Pharmacogenetics and Genomics 21, 206-216.

Majic,T., Rentzsch,J., Gudlowski,Y., Ehrlich,S., Juckel,G., Sander,T., Lang,U.E., Winterer,G., and Gallinat,J. (2011). COMT Val(108/158)Met genotype modulates human sensory gating. Neuroimage 55, 818-824.

Pernhorst,K., Raabe,A., Niehusmann,P., van Loo,K.M.J., Grote,A., Hoffmann,P., Cichon,S., Sander,T., Schoch,S., and Becker,A.J. (2011). Promoter Variants Determine gamma-Aminobutyric Acid Homeostasis-Related Gene Transcription in Human Epileptic Hippocampi. Journal of Neuropathology and Experimental Neurology 70, 1080-1088.

 

2010

Budde,H., Sander,T., Wernicke,C., Muller,A., Gallinat,J., Schmidt,L.G., and Smolka,M.N. (2010). Serotonin transporter promoter polymorphism and dopaminergic sensitivity in alcoholics. J Neural Transm. 117, 133-138.

Chioza,B.A., Aicardi,J., Aschauer,H., Brouwer,O., Callenbach,P., Covanis,A., Dooley,J.M., Dulac,O., Durner,M., Eeg-Olofsson,O., Feucht,M., Friis,M.L., Guerrini,R., Kjeldsen,M.J., Nabbout,R., Nashef,L., Sander,T., Siren,A., Wirrell,E., McKeigue,P., Robinson,R., Gardiner,R.M., and Everett,K.V. (2009). Genome wide high density SNP-based linkage analysis of childhood absence epilepsy identifies a susceptibility locus on chromosome 3p23-p14. Epilepsy Res. 87, 247-255.

de Kovel,C.G., Pinto,D., Tauer,U., Lorenz,S., Muhle,H., Leu,C., Neubauer,B.A., Hempelmann,A., Callenbach,P.M., Scheffer,I.E., Berkovic,S.F., Rudolf,G., Striano,P., Siren,A., Baykan,B., Sander,T., Lindhout,D., Kasteleijn-Nolst Trenite,D.G., Stephani,U., and Koeleman,B.P. (2010). Whole-genome linkage scan for epilepsy-related photosensitivity: a mega-analysis. Epilepsy Res. 89, 286-294.

de Kovel,C.G., Trucks,H., Helbig,I., Mefford,H.C., Baker,C., Leu,C., Kluck,C., Muhle,H., von,S.S., Ostertag,P., Obermeier,T., Kleefuss-Lie,A.A., Hallmann,K., Steffens,M., Gaus,V., Klein,K.M., Hamer,H.M., Rosenow,F., Brilstra,E.H., Trenite,D.K., Swinkels,M.E., Weber,Y.G., Unterberger,I., Zimprich,F., Urak,L., Feucht,M., Fuchs,K., Moller,R.S., Hjalgrim,H., De,J.P., Suls,A., Ruckert,I.M., Wichmann,H.E., Franke,A., Schreiber,S., Nurnberg,P., Elger,C.E., Lerche,H., Stephani,U., Koeleman,B.P., Lindhout,D., Eichler,E.E., and Sander,T. (2010). Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies. Brain. 133, 23-32.

Giegling,I., Drago,A., Dolzan,V., Plesnicar,B.K., Schafer,M., Hartmann,A.M., Sander,T., Toliat,M.R., Moller,H.J., Stassen,H.H., Rujescu,D., and Serretti,A. (2010). Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol. Pharmacogenet Genomics. [Epub ahead of print]

Li,S.C., Chicherio,C., Nyberg,L., von,O.T., Nagel,I.E., Papenberg,G., Sander,T., Heekeren,H.R., Lindenberger,U., and Backman,L. (2010). Ebbinghaus revisited: influences of the BDNF Val66Met polymorphism on backward serial recall are modulated by human aging. J Cogn Neurosci. 22, 2164-2173.

Muhle,H., von,S.S., Gaus,V., Kara,S., Helbig,I., Hampe,J., Franke,A., Weber,Y., Lerche,H., Kleefuss-Lie,A.A., Elger,C.E., Schreiber,S., Stephani,U., and Sander,T. (2010). Role of GRM4 in idiopathic generalized epilepsies analysed by genetic association and sequence analysis. Epilepsy Res. 89, 319-326.

Opgen-Rhein,C., Brandl,E.J., Muller,D.J., Neuhaus,A.H., Tiwari,A.K., Sander,T., and Dettling,M. (2010). Association of HTR2C, but not LEP or INSIG2, genes with antipsychotic-induced weight gain in a German sample. Pharmacogenomics. 11, 773-780.

Preuschhof,C., Heekeren,H.R., Li,S.C., Sander,T., Lindenberger,U., and Backman,L. (2010). KIBRA and CLSTN2 polymorphisms exert interactive effects on human episodic memory. Neuropsychologia. 48, 402-408.

Steffens,M., Becker,T., Sander,T., Fimmers,R., Herold,C., Holler,D.A., Leu,C., Herms,S., Cichon,S., Bohn,B., Gerstner,T., Griebel,M., Nothen,M.M., Wienker,T.F., and Baur,M.P. (2010). Feasible and successful: genome-wide interaction analysis involving all 1.9 x 10(11) pair-wise interaction tests. Hum Hered. 69, 268-284.

von Spizczak,S., Muhle,H., Helbig,I., de Kovel,C.G., Hampe,J., Gaus,V., Koeleman,B.P., Lindhout,D., Schreiber,S., Sander,T., and Stephani,U. (2010). Association study of TRPC4 as a candidate gene for generalized epilepsy with photosensitivity. Neuromolecular. Med. 12, 292-299.

 

2009

Chioza BA, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dooley JM, Dulac O, Durner M, Eeg-Olofsson O, Feucht M, Friis ML, Guerrini R, Kjeldsen MJ, Nabbout R, Nashef L, Sander T, Sirén A, Wirrell E, McKeigue P, Robinson R, Gardiner RM, Everett KV (2009) Genome wide high density SNP-based linkage analysis of childhood absence epilepsy identifies a susceptibility locus on chromosome 3p23-p14. Epilepsy Res 87: 247-55.

Dibbens LM, Mullen S, Helbig I, Mefford MC, BaylyMA, Bellows S, Leu C, Trucks H, Obermeier T, Wittig M, Franke A, Caglayan H, Yapici Z, EPICURE Consortium, Sander T, Eichler EE, Scheffer IE, Mulley JC, Berkovic SF (2009). Familial and sporadic 15q13.3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance. Hum Mol Genet 18: 3626–31.

Helbig I, Mefford HC, Sharp AJ, Guipponi M, Fichera M, Franke A, Muhle H, de Kovel C, Baker C, von Spiczak S, Kron KL, Steinich I, Kleefuß-Lie AA, Leu C, Gaus V, Schmitz B, Kein KM, Reif PS, Rosenow F, Weber Y, Lerche H, Zimprich F, Urak L, Fuchs K, Feucht M, Genton P, Thomas P, Visscher1 F, de Haan GJ, Møller RS, Hjalgrim H, Luciano D, Wittig M, Nothnagel M, Elger CE, Nürnberg P, Romano C, Malafosse A, Koeleman BPC, Lindhout D, Stephani U, Schreiber S, Eichler EE, Sander T (2009) 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy. Nat Genet 1: 160-162.

Lang UE, Hellweg R, Sander T, Gallinat J (2009) The Met allele of the BDNF Val66Met polymorphism is associated with increased BDNF serum concentrations. Mol Psychiatry 14: 120–122.

Neuhaus AH, Opgen-Rhein C, Urbanek C, Hahn E, Ta TM, Seidelsohn M, Strathmann S, Kley F, Wieseke N, Sander T, Dettling M (2009) COMT Val158Met polymorphism is associated with cognitive flexibility in a signal discrimination task in schizophrenia. Pharmacopsychiatry 42: 141-4.

 

2008

Lang UE, Hellweg R, Bajbouj M, Gaus V, Sander T, Gallinat J (2008) Gender-dependent association of a functional NGF polymorphism with anxiety-related personality traits. Pharmacopsychiatry 5: 196-199.

Lohoff FW, Lautenschlager M, Mohr J, Ferraro TN, Sander T, Gallinat J (2008) Association between variation in the vesicular monoamine transporter 1 gene on chromosome 8p and anxiety-related personality traits. Neurosci Lett 1: 41-45.

Nagel IE, Chicherio C, Li SC, von Oertzen T, Sander T, Villringer A, Heekeren HR, Bäckman L, Lindenberger U (2008) Human aging magnifies genetic effects on executive functioning and working memory. Front Hum Neurosci 2: 1, Epub 2008 May 3.

Neubauer BA, Waldegger S, Heinzinger J, Hahn A, Kurlemann G, Fiedler B, Eberhard F, Muhle H, Stephani U, Garkisch S, Eeg-Olofsson O, Muller U, Sander T (2008) KCNQ2 and KCNQ3 mutations contribute to different idiopathic epilepsy syndromes. Neurology 3: 177-183.

Opgen-Rhein C, Neuhaus AH, Urbanek C, Hahn E, Sander T, Dettling M (2008) Executive Attention in Schizophrenic Males and the Impact of COMT Val108/158Met Genotype on Performance on the Attention Network Test. Schizophr Bull 6: 1231-1239.

Schmack K, Schlagenhauf F, Sterzer P, Wrase J, Beck A, Dembler T, Kalus P, Puls I, Sander T, Heinz A, Gallinat J (2008) Catechol-O-methyltransferase val158met genotype influences neural processing of reward anticipation. Neuroimage 4: 1631-1638.

Tang B, Sander T, Craven KB, Hempelmann A, Escayg A (2008) Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy. Neurobiol Dis 1: 59-70.

 

2007

Cavalleri GL, Walley NM, Soranzo N, Mulley J, Doherty CP, Kapoor A, Depondt C, Lynch JM, Scheffer IE, Heils A, Gehrmann A, Kinirons P, Gandhi S, Satishchandra P, Wood NW, Anand A, Sander T, Berkovic SF, Delanty N, Goldstein DB, Sisodiya SM (2007) A multicenter study of BRD2 as a risk factor for juvenile myoclonic epilepsy. Epilepsia 4: 706-712.

Everett K, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dooley J, Dulac O, Durner M, Eeg-Olofsson O, Feucht M, Friis M, Guerrini R, Heils A, Kjeldsen M, Nabbout R, Sander T, Wirrell E, McKeigue P, Robinson R, Taske N, Gardiner M (2007) Linkage and mutational analysis of CLCN2 in childhood absence epilepsy. Epilepsy Res 2-3: 145-153.

Everett KV, Chioza B, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dulac O, Eeg-Olofsson O, Feucht M, Friis M, Goutieres F, Guerrini R, Heils A, Kjeldsen M, Lehesjoki AE, Makoff A, Nabbout R, Olsson I, Sander T, Siren A, McKeigue P, Robinson R, Taske N, Rees M, Gardiner M (2007) Linkage and association analysis of CACNG3 in childhood absence epilepsy. Eur J Hum Genet 4: 463-472.

Gallinat J, Gotz T, Kalus P, Bajbouj M, Sander T, Winterer G (2007) Genetic variations of the NR3A subunit of the NMDA receptor modulate prefrontal cerebral activity in humans. J Cogn Neurosci 1: 59-68.

Hempelmann A, Cobilanschi J, Heils A, Muhle H, Stephani U, Weber Y, Lerche H, Sander T (2007) Lack of evidence of an allelic association of a functional GABRB3 exon 1a promoter polymorphism with idiopathic generalized epilepsy. Epilepsy Res 1: 28-32.

Lang UE, Bajbouj M, Sander T, Gallinat J (2007) Gender-dependent association of the functional catechol-O-methyltransferase Val158Met genotype with sensation seeking personality trait. Neuropsychopharmacology 9: 1950-1955.

Lang UE, Sander T, Lohoff FW, Hellweg R, Bajbouj M, Winterer G, Gallinat J (2007) Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking. Psychopharmacology (Berl) 4: 433-439.

Leach NT, Sun Y, Michaud S, Zheng Y, Ligon KL, Ligon AH, Sander T, Korf BR, Lu W, Harris DJ, Gusella JF, Maas RL, Quade BJ, Cole AJ, Kelz MB, Morton CC (2007) Disruption of diacylglycerol kinase delta (DGKD) associated with seizures in humans and mice. Am J Hum Genet 4: 792-799.

Lorenz S, Heils A, Sander T (2007) Allelic association of a truncation mutation of the KCNMB3 gene with idiopathic generalized epilepsy. Am J Med Genet B Neuropsychiatr Genet 1: 10-13.

Winterer G, Musso F, Konrad A, Vucurevic G, Stoeter P, Sander T, Gallinat J (2007) Association of attentional network function with exon 5 variations of the CHRNA4 gene. Hum Mol Genet 18: 2165-2174.

 

2006

Brevern M, Ta N, Wiste A, Siegel A, Sander T, Radtke A, Escayg A (2006) Migrainous vertigo: Mutation analysis of CACNA1A, CACNB4 and ATP1A2. Headache 7: 1136-1141.

Chioza B, Everett K, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dulac O, Durner M, Eeg-Olofsson O, Feucht M, Friis M, Heils A, Kjeldsen M, Larsson K, Lehesjoki AE, Nabbout R, Olsson I, Sander T, Siren A, Robinson R, Rees M, Gardiner RM (2006) Evaluation of CACNA1H in European patients with childhood absence epilepsy. Epilepsy Res 69:177-181.

Fehr C, Sander T, Tadic A, Lenzen KP, Anghelescu I, Klawe C, Dahmen N, Schmidt LG, Szegedi A (2006) Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis. Psychiatr Genet 16:9-17.

Gallinat J, Götz T, Kalus P, Bajbouj M, Sander T, Winterer G (2006) Genetic variations of the NR3A subunit of the NMDA receptor modulate prefrontal cerebral activity in humans. J Neurocognition, in press

Hempelmann A, Heils A, Sander T (2006) Confirmatory evidence for an association of the connexin 36 gene with juvenile myoclonic epilepsy. Epilepsy Res, in press

Hempelmann A, Kumar S, Muralitharan S, Sander T (2006) Myofibrillogenesis regulator 1 gene (MR-1) mutation in an Omani family with paroxysmal nonkinesigenic dyskinesia. Neurosci Lett 402:118-120.

Hempelmann A, Lenzen KP, Heils A, Lorenz S, Prud’Homme JF, Nabbout R, Dulac O, Rudolf G, Zara F, Bianchi A, Robinson R, Gardiner MR, Covanis A, Lindhout D, Stephani U, Elger CE, Weber YG, Lerche H, Nürnberg P, Kron K, Scheffer IE, Mulley JC, Berkovic SF, Sander T (2006) Exploration of the Genetic Architecture of Idiopathic Generalized Epilepsies. Epilepsia 10: 1682-1690.

Kirchheiner J, Lang UE, Stamm T, Sander T, Gallinat (2006) Association of CYP2D6 genotypes and personality traits in healthy individuals. J Clin Psychopharmacol 4: 440-442.

Lohoff FW, Dahl JP, Ferraro TN, Arnold SE, Gallinat J, Sander T, Berrettini WH (2006) Variations in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) are associated with bipolar disorder. Neuropsychopharmacology 12: 2739-2747

Lorenz S, Heils A, Taylor KP, Gehrmann A, Schmitz B, Muhle H, Gresch M, Becker T, Tauer U, Stephani U, Sander T (2006) Candidate gene analysis of the succinic semialdehyde dehydrogenase gene (ALDH5A1) in patients with idiopathic generalized epilepsy and photosensitivity. Neurosci Lett 397:234-239.

Lorenz S, Taylor KP, Gehrmann A, Becker T, Muhle H, Gresch M, Tauer U, Sander T, Stephani U (2006) Association of BRD2 polymorphisms with photoparoxysmal response. Neurosci Lett 400:135-139.

 

2005

Bertrand D, Elmslie F, Hughes E, Trounce J, Sander T, Bertrand S, Steinlein OK (2005) The CHRNB2 mutation I312M is associated with epilepsy and distinct memory deficits. Neurobiol Dis 20:799-804.

Gu W, Sander T, Heils A, Lenzen KP, Steinlein OK (2005) A new EF-hand containing gene EFHC2 on Xp11.4: evidence for association with juvenile myoclonic epilepsy. Epilepsy Res, 66:91-98.

Lang U, Hellweg R, Bajbouj M, Lenzen KP, Sander T, Kunz D, Gallinat J (2005) Association of a functional BDNF polymorphism and anxiety-related personality traits. Psychopharmacology (Ber.) 180: 95-99.

Lenzen KP, Heils A, Lorenz S, Hempelmann A, Höfels S, Lohoff FW, Schmitz B, Sander T (2005) Supportive evidence for an allelic association of the human KCNJ10 potassium channel gene with idiopathic generalized epilepsy. Epilepsy Res 63: 113-118.

Lenzen KP, Heils A, Lorenz S, Hempelmann A, Höfels S, Sander T (2005) Association analysis of the Arg220His variation of the human gene encoding the GABA delta subunit with idiopathic generalized epilepsy. Epilepsy Res 65: 53-57.

Lenzen KP, Heils A, Lorenz S, Hempelmann A, Sander T (2005) Association analysis of the malic enzyme 2 gene polymorphisms with idiopathic generalized epilepsy. Epilepsia 46:1637-1641.

Lohoff FW, Ferraro TN, Sander T, Zhao H, Dahl JP, Berrettini WH, Buono RJ (2005) No association between common variations in the human alpha 2 subunit gene (ATP1A2) of the sodium potassium transporting ATPase and idiopathic generalized epilepsy. Neurosci Lett 382:33-38.

Lohoff FW, Sander T, Ferraro TN, Dahl JP, Gallinat J, Berrettini WH (2005) Confirmation of association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and bipolar I disorder. Am J Med Genet (Neuropsychiatr Genet) 139:51-53.

Neubauer BA, Waltz S, Grothe M, Hahn A, Tuxhorn I, Sander T, Kurlemann G, Stephani U (2005) Photosensitivity: genetics and clinical significance. Adv Neurol 95: 217-226.

Schmitt B, Wohlrab G, Sander T, Steinlein OK, Hajnal BL (2005) Neonatal seizures with tonic clonic sequences and poor developmental outcome. Epilepsy Res 65:161-168.

Tadic A, Dahmen N, Szegedi A, Rujescu D, Giegling I, Koller G, Anghelescu IG, Fehr C, Klawe C, Preuss UW, Sander T, Toliat MR, Singer P, Bondy B, Soyka M (2005) Polymorphisms in the NMDA subunit 2B are not associated with alcohol dependence and alcohol withdrawal-induced seizures and delirium tremens. Eur Arch Psychiatry Clin Neurosci 255: 129-135.

Tauer U, Lorenz S, Lenzen KP, Heils A, Muhle H, Gresch M, Neubauer B, Waltz S, Rudolf G, Mattheisen M, Strauch K, Nürnberg P, Schmitz B, Stephani U, Sander T (2005). Genetic dissection of photosensitivity and its relation to idiopathic generalized epilepsy. Ann Neurol 57: 866-873.

 

2004

Buono RJ, Lohoff FW, Sander T, Sperling MR, O'Connor MJ, Dlugos DJ, Ryan SG, Golden GT, Zhao H, Scattergood TM, Berrettini WH, Ferraro TN (2004) Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility. Epilepsy Res 58: 175-183.

Dettling M, Sander T, Weber M, Steinlein OK (2004) Mutation analysis of the ryanodine receptor gene isoform 3 (RYR3) in recurrent neuroleptic malignant syndrome. J Clin Psychopharmacol 24: 471-473.

Gu W, Sander T, Becker T, Steinlein OK (2004) Genotypic association of exonic LGI4-polymorphisms and childhood absence epilepsy. Neurogenetics 5: 41-44.

 

2003

Gallinat J, Bajbouj M, Sander T, Schlattmann P, Xu K, Ferro EF, Goldman D, Winterer G (2003) Association of the G1947A COMT (Val(108/158)Met) gene polymorphism with prefrontal P300 during information processing. Biol Psychiatry 54: 40-48.

Gallinat J, Senkowski D, Wernicke C, Juckel G, Becker I, Sander T, Smolka M, Hegerl U, Rommelspacher H, Winterer G, Herrmann WM (2003) Allelic Variants of the Functional Promoter Polymorphism of the Human Serotonin Transporter Gene is Associated with Auditory Cortical Stimulus Processing. Neuropsychopharmacology 28: 530-532.

Izzi C, Barbon A, Toliat RM, Heils A, Becker C, Nürnberg P, Sander T, Barlati S (2003) Candidate gene analysis of the human metabotropic glutamate receptor type 4 (GRM4) in patients with juvenile myoclonic epilepsy. Am J Med Genet 123B: 59-63.

Sander T, Windemuth C, Schulz H, Saar K, Gennaro E, Riggio C, Bianchi A, Zara F, Rudolf G, Picard F, Bulteau C, Kaminska A, Cieuta C, Prud'homme J-F, Dulac O, Bate L, Robinson R, Gardiner RM, Covanis A, de Haan G-J, Janssen AMAJ, van Erp MG, Boezeman EHFJ, Lindhout D, Heils A, Nürnberg P, Janz D (2003) Exploration of a putative susceptibility locus for idiopathic generalized epilepsy on chromosome 8p12. Epilepsia 44: 32-39.

Winterer G, Smolka M, Samochowiec J, Malberg R, Gallinat J, Rommelspacher H-P, Herrmann WM, Schmidt LG, Sander T (2003) Association Analysis of exonic variants of the GABAB receptor gene and alpha EEG-voltage in normals and patients with alcoholism. Am J Med Genet 117B: 51-56.

 

2002

Izzi C, Barbon A, Kretz R, Sander T, Barlati S (2002) Sequencing of the GRIK1 gene in patients with juvenile absence epilepsy does not reveal mutations affecting receptor structure. Am J Med Genet 114: 354-359

Kananura C, Haug K, Sander T, Runge U, Gu W, Hallmann K, Rebstock J, Heils A, Steinlein OK (2002) A splice-donor-site mutation in GABRG2 causes childhood absence epilepsy and febrile convulsions. Arch Neurol 59: 1137-1141.

Kananura C, Sander T, Rajan S, Preisig-Müller R, Grzeschik K-H, Daut J, Derst C, Steinlein OK (2002) The tandem pore domain K+ channel TASK-3 (KCNK9) and idiopathic absence epilepsies. Am J Med Genet 114: 227-229.

Robinson R , Taske N, Heils A, Sander T, Whitehouse W, Goutières F, Aicardi J, Lehesjoki A-E, Friis ML, Kjeldsen MJ, Panayiotopoulos C, Kennedy C, Ferrie C, Rees M, Gardiner RM (2002) Linkage analysis between childhood absence epilepsy and genes encoding GABAA and GABAB receptors, voltage-dependent calcium channels, and the ECA1 region on chromosome 8q. Epilepsy Res 48: 169-179

Sander T, Toliat MR, Heils A, Becker C, Nürnberg P (2002) Failure to replicate an allelic association between an exon 8 polymorphism of the human ?1A calcium channel gene and common syndromes of idiopathic generalized epilepsy. Epilepsy Res 49: 173-177.

Sander T, Toliat MR, Heils A, Leschik G, Becker C, Rüschendorf F, Rohde K, Mundlos S, Nürnberg P (2002) Mutation analysis of the human anion exchanger 3 gene in patients with familial idiopathic generalized epilepsy. Epilepsy Res 51: 249-255.

Sander T, Windemuth C, Schulz H, Saar K, Gennaro E, Riggio C, Bianchi A, Zara F, Luna D, Bulteau C, Kaminska A, Ville D, Cieuta C, Picard F, Prud'homme J-F, Dulac O, Bate L, Gardiner RM, de Haan G-J, Janssen AMAJ, van Erp MG, Boezeman EHFJ, Lindhout D, Wienker TF, Heils A, Nürnberg P, Reis A, Janz D (2002) No evidence for a susceptibility locus for idiopathic generalized epilepsy on chromosome 18q21.1. Am J Med Genet 114: 673-678

Windemuth C, Schulz H, Saar K, Gennaro E, Riggio C, Bianchi A, Zara F, Luna D, Bulteau C, Kaminska A, Ville D, Cieuta C, Prud'homme J-F, Dulac O, Bate L, Gardiner RM, Covanis A, Lindhout D, Wienker TF, Janz D, Sander T (2002) No evidence for a susceptibility locus for idiopathic generalized epilepsy on chromosome 5 in families with typical absence seizures. Epilepsy Res 5: 23-29.

 

2000

Escayg A, De Waard M, Lee DD, Wolf P, Mayer T, Baloh R, Sander T, Meisler MH (2000) Mutations of the human ß4 subunit gene CACNB4 in idiopathic generalized epilepsy and episodic ataxia. Am J Hum Genet 66: 1531-1539.

Franke P, Nöthen MM, Wang T, Knapp M, Lichtermann D, Neidt H, Sander T, Propping P, Maier W (2000) DRD4 exon III VNTR polymorphism – susceptibility factor for heroin dependence ? Results of a case-control and a family-based association approach. Mol Psychiatry 5: 101-104.

Gasser T, Dichgans M, Jurkat-Rott K, Klockgether T, Klopstock T, Kretschmar H, Lehmann-Horn F, Reichmann H, Rolfs A, Sander T, Stogbauer F (2000) Positionspapier: Molekulare Diagnostik erblicher neurologischer Erkrankungen. Nervenarzt 71: 774-796.

Gscheidel N, Sander T, Wendel B, Heere P, Samochowiec J, Schmidt LG, Rommelspacher H, Hoehe MR (2000) Five µ opioid receptor exon 1 variants and vulnerability to alcohol dependence. Pol J Pharmacol 52: 27-31

Hallmann K, Durner M, Sander T, Steinlein OK (2000) Mutation analysis of the inwardly rectifying K+ channels KCNJ6 (GIRK2) and KCNJ3 (GIRK1) in juvenile myoclonic epilepsy. Am J Med Genet 96: 8-11.

Haug K, Hallmann K, Horvath S, Sander T, Kubisch C, Rau B, Dullinger J, Beyenburg S, Elger CE, Propping P, Heils A (2000) No evidence for association between the KCNQ3 gene and susceptibility to idiopathic generalized epilepsy. Epilepsy Res 42: 57-62.

Haug K, Kremerskothen J, Hallmann K, Sander T, Dullinger J, Rau B, Beyenburg S, Lentze MJ, Barnekow A, Elger CE, Propping P, Heils A (2000) Mutation screening of the chromosome 8q24.3-human “activity-regulated cytoskeleton-associated gene” (ARC) in idiopathic generalized epilepsy. Mol Cell Probes 14: 255-260.

Haug K, Sander T, Hallmann K, Lentze MJ, Propping P, Elger CE, Heils A (2000) Association analysis between a regulatory promoter polymorphism of the human monoamino oxidase A gene and idiopathic generalized epilepsy. Epilepsy Res 39: 127-132.

Haug K, Sander T, Hallmann K, Rau B, Dullinger J, Elger CE, Propping P, Heils A (2000) The voltage-gated sodium channel beta-2-subunit gene and idiopathic generalized epilepsy. Neuroreport 12: 2687-2689.

Sand PG, Godau C, Riederer P, Peters C, Franke P, Nothen M, Stober G, Fritze J, Maier W, Propping P, Lesch KP, Riess O, Sander T, Beckmann H, Deckert J (2000) Exonic variants of the GABAB receptor gene and panic disorder. Psychiatr Genet 10: 191-194.

Sander T, Berlin W, Gscheidel N, Wendel B, Janz D, Hoehe MR (2000) Genetic variation of the human ?-opioid receptor and susceptibility to idiopathic absence epilepsy. Epilepsy Res 39: 57-61.

Sander T, Berlin W, Ostapowicz A, Samochowiec J, Janz D, Gscheidel N, Hoehe MR (2000) Variation of the genes encoding the human glutamate EAAT2, serotonin and dopamine transporters and susceptibility to idiopathic generalized epilepsy. Epilepsy Res 41: 75-81

Sander T, Ostapowicz A, Samochowiec J, Smolka M, Rommelspacher H, Winterer G, Schmidt LG (2000) Evaluation of an allelic association of the serotonin 5-HT1B G681C polymorphism with antisocial alcoholism in the German population. Addiction Biol 5: 167-172.

Sander T, Ostapowicz A, Samochowiec J, Smolka M, Winterer G, Schmidt LG (2000) Genetic variation of the glutamate transporter EAAT2 gene and vulnerability to alcohol dependence. Psychiatr Genet 10:103-107.

Sander T, Schulz H, Saar K, Gennaro E, Riggio C, Bianchi A, Zara F, Picard F, Cieuta C, Ville D, Nabbout R, Prud'homme J-F, Dulac O, Bate L, Sundquist A, Gardiner RM, Janssen AMAJ, de Haan G-J, Kasteleijn-Nolst-Trenité DGA, Bader A, Lindhout D, Riess O, Wienker TF, Janz D, Reis A (2000) Genome search for susceptibility loci of common idiopathic generalised epilepsies. Hum Mol Genet 9: 1465-1472.

Schmidt LD, Sander T (2000) Genetics of alcohol withdrawal. Eur Psychiatry 15: 135-139.

Schmidt LG, Sander T, Kuhn S, Smolka M, Samochowiec J, Rommelspacher H, Lesch KP (2000) Different allele distribution of a regulatory MAOA gene promoter polymorphism in antisocial and anxious-depressive alcoholics. J Neural Trans 107: 681-689.

Winterer G, Smolka M, Samochowiec J, Mulert C, Ziller M, Mahlberg R, Wuebben Y, Herrmann WM, Sander T (2000) Association Analysis of GABAA ?2 and ?2 gene polymorphism with event-related prefrontal activity in man. Hum Genet 107:513-518.

 

1999 and later

Samochowiec J, Rottmann M, Okladnova O, Syagailo Y, Sander T, Mühlbauer E, Smolka M, Tranitz M, Winterer G, Rommelspacher H, Schmidt LG, Lesch KP (1999) Association analysis of a regulatory promoter polymorphism of the PAX-6 gene with alcohol dependence. Addiction Biology 4: 323-328

Samochowiec J, Smolka M, Winterer G, Rommelspacher H, Schmidt LG, Sander T (1999) Association analysis between a Cys23Ser substitution polymorphism within the human 5-HT2c receptor gene and neuronal hyperexcitability. Am J Med Genet 88: 126-130

Sander T, Ball D, Murray R, Patel J, Samochowiec J, Smolka M, Winterer G, Rommelspacher H, Schmidt LG, Loh E-W (1999) Association analysis of sequence variants of the GABAA ?6, ?2, and ?2 gene cluster and alcohol dependence. Alcohol Clin Exp Res 23: 427-431

Sander T, Ladehoff M, Samochowiec J, Finckh U, Rommelspacher H, Schmidt LG (1999) Lack of an allelic association between polymorphisms of the dopamine D2 Receptor gene and alcohol dependence in the German population. Alcohol Clin Exp Res 23: 578-581

Sander T, Peters C, Kämmer G, Samochowiec J, Zirra M, Mischke D, Ziegler A, Kaupmann K, Bettler B, Epplen JT, Riess O (1999) Association analysis of exonic variants of the gene encoding the GABAB Receptor and idiopathic generalized epilepsy. Am J Med Genet 88: 305-310

Sander T, Samochowiec J, Ladehoff M, Peters C, Riess O, Rommelspacher H, Schmidt LG (1999) Association analysis of exonic variants of the gene encoding the GABAB receptor and alcohol dependence. Psychiatr Genet 9: 69-73

Sander T, Schölz L, Janz D, Epplen JT, Rieß O (1999) Length variation of a polyglutamine array in the gene encoding a small-conductance, calcium-activated potassium channel (hKCa3) and susceptibility to idiopathic generalized epilepsy. Epilepsy Res 33: 227-233

Sander T, Schulz H, Vieira-Saeker AMM, Bianchi A, Sailer U, Bauer G, Scaramelli A, Wienker TF, Saar K, Reis A, Janz D, Epplen JT, Rieß O (1999) The confirmation analysis of a putative major susceptibility locus for juvenile myoclonic epilepsy on chromosome 15q14. Am J Med Genet 88: 182-187

Sander T, Syagailo Y, Samochowiec J, Okladnova O, Lesch KP, Janz D (1999) Association analysis of a regulatory promoter polymorphism of the PAX-6 gene with idiopathic generalized epilepsy. Epilepsy Res 36: 61-67

Smolka M, Sander T, Schmidt LG, Samochowiec J, Rommelspacher H, Gscheidel N, Wendel B, Hoehe M (1999) Dopaminergic sensitivity and µ-opioid receptor variants in alcoholics. Psychoneuroendocrinology 24: 629-638

Steinlein OK, Stoodt J, Biervert C, Janz D, Sander T (1999) The voltage gated potassium channel KCNQ2 and idiopathic generalized epilepsy. Neuroreport 10: 1163-1166

1998

Hoehe MR, Wendel B, Chiaroni P, Levy N, Morris-Rosendahl D, Macher J-P, Sander T, Crocq M-A (1998) Serotonin transporter (5-HTT) gene polymorphisms are not associated with susceptibility to mood disorder. Am J Med Genet 81: 1-3

Peters C, Kämmer G, Volz A, Kaupmann K, Ziegler A, Bettler B, Epplen JT, Sander T, Riess O (1998) Precise mapping and genomic structure of the human GABABR1 receptor gene; no evidence of a major involvement in idiopathic generalized epilepsy. Neurogenetics 2: 47-54

Sander T, Gscheidel N, Wendel B, Samochowiec J, Smolka M, Rommelspacher H, Schmidt LG, Hoehe M (1998) Human ?-opioid receptor variation and alcohol dependence. Alcohol Clin Exp Res 22: 2108-2110

Sander T, Harms H, Lesch KP, Dufeu P, Kuhn S, Hoehe M, Rommelspacher H, Schmidt LG (1998) Serotonin transporter gene variants in alcohol-dependent subjects with dissocial personality disorder. Biol Psychiatry 43: 908-912

Sander T, Harms H, Rommelspacher H, Hoehe M, Schmidt LG (1998) Possible allelic association of a tyrosine hydroxylase polymorphism with vulnerability to alcohol withdrawal delirium. Psychiatr Genet 8: 13-17

Sander T, Kretz R, Schulz H, Sailer U, Bauer G, Scaramelli A, Epplen JT, Rieß O, Janz D (1998) Replication analysis of a putative susceptibility locus (EGI) for idiopathic generalized epilepsy on chromosome 8q24. Epilepsia 39: 715-720

Sander T, Neubauer B, Steinlein O (1998) Genetik der Epilepsie. Medizinische Genetik 10: 383-386

Sander T, Peters C, Janz D, Bianchi A, Bauer G, Wienker TF, Hildmann T, Epplen JT, Rieß O (1998) The gene encoding the ?1A-voltage-dependent calcium channel (CACN1A4) is not causative in the etiology of common subtypes of idiopathic generalized epilepsy. Epilepsy Res 29: 115-120

Schmidt LG, Harms H, Kuhn S, Rommelspacher H, Sander T (1998) Withdrawal symptoms are pronounced in alcoholics carrying the A9 allele of the dopamine transporter gene. Am J Psychiatry 155: 474-478

1997

Delbrück S, Wendel B, Sander T, Morris-Rosendahl D, Crocq M-A, Berretini WH, Hoehe MR (1997) A novel allelic variant of the serotonin transporter gene regulatory polymorphism. Cytogenet Cell Genet 79: 214-220

Finckh U, Kuhn S, Dufeu P, Otto G, Heinz A, Dettling M, Giraldo-Velasquez M, Pelz J, Gräf K-J, Harms H, Sander T, Rommelspacher H, Schmidt LG, Rolfs A (1997) Influence of the dopamine D2 receptor (DRD2) genotype on neuropharmacological effects of alcohol and the clinical outcome of alcoholism. Pharmacogenetics 7: 271-281

Sander T, Bockenkamp B, Hildmann T, Blasczyk R, Kretz R, Wienker TF, Volz A, Schmitz B, Beck-Mannagetta G, Rieß O, Epplen JT, Janz D, Ziegler A (1997) Refined mapping of the epilepsy susceptibility locus EJM1 on chromosome 6. Neurology 49: 842-847

Sander T, Harms H, Dufeu P, Kuhn S, Rommelspacher H, Schmidt LG (1997) Dopamine D4 receptor exon III alleles and variation of novelty seeking in alcoholics. Am J Med Genet 74: 483-487

Sander T, Harms H, Lesch KP, Dufeu P, Kuhn S, Hoehe M, Rommelspacher H, Schmidt LG (1997) Association analysis of a regulatory variant of the serotonin transporter gene with severe alcohol dependence. Alcohol Clin Exp Res, 21: 1356-1359

Sander T, Harms H, Podschus J, Finckh U, Nickel B, Rolfs A, Rommelspacher H, Schmidt LG (1997) Allelic association of a dopamine transporter gene polymorphism in alcohol dependence with withdrawal seizures or delirium. Biol Psychiatry 41: 299-304

Sander T, Hildmann T, Kretz R, Fürst R, Sailer U, Bauer G, Schmitz B, Beck-Mannagetta G, Wienker T, Janz D (1997) Allelic association of juvenile absence epilepsy with a GluR5 kainate receptor gene (GRIK1) polymorphism. Am J Med Genet 74: 416-421

Sander T, Kretz R, Williamson MP, Elmslie FV, Rees M, Hildmann T, Bianchi A, Bauer G, Sailer U, Scaramelli A, Schmitz B, Gardiner RM, Janz D, Beck-Mannagetta G (1997) Linkage analysis between idiopathic generalized epilepsies and the GABAA receptor ?5, ß3 and ?3 subunit gene cluster on chromosome 15. Acta Scand Neurol 96: 1-5

Steinlein O, Sander T, Stoodt J, Kretz R, Janz D, Propping P (1997) Possible association of a silent polymorphism in the neuronal nicotinic acetylcholine receptor subunit ?4 with common idiopathic generalized epilepsies. Am J Med Genet 74: 445-449

1996

Finckh U, Giraldo-Velasquez M, Pelz J, Otto G, Sander T, Harms H, Schmidt LG, Rommelspacher H, Rolfs A (1996) Dopamine D2 receptor gene (DRD2) haplotypes in Caucasians. Gene 179: 251-255

Finckh U, v Widdern O, Giraldo-Velasquez M, Podschus J, Dufeu P, Sander T, Harms H, Schmidt LG, Rommelspacher H, Rolfs A (1996) No association of the structural dopamine D2 receptor (DRD2) variant 311cys with alcoholism. Alcohol Clin Exp Res 20: 528-532

Heinz A, Sander T, Harms H, Finckh U, Dufeu P, Kuhn S, Dettling M, Gräf K, Rolfs A, Rommelspacher, H, Schmidt LG (1996) Lack of allelic association of dopamine D1 and D2 receptor gene polymorphisms with reduced dopaminergic sensitivity in alcoholism. Alcohol Clin Exp Res 20: 1109-1113

Sander T (1996) The genetics of idiopathic generalized epilepsy: implications for the understanding of its aetiology. Mol Med Today 2: 173-180

Sander T, Hildmann T, Janz D, Bianchi A, Bauer G, Scaramelli A, Beck-Mannagetta G (1996) Lack of linkage between idiopathic generalized epilepsies and the gene encoding the neural adhesion molecule. Epilepsy Res, 25: 139-145

Sander T, Hildmann T, Janz D, Wienker TF, Bianchi A, Bauer G, Sailer U, Berek K, Scaramelli A Neitzel H, Schmitz B, Bailey MES, Beck-Mannagetta G, Johnson KJ, Darlison MG (1996) Exclusion of linkage between idiopathic generalized epilepsies and the GABAA receptor ?1 and ?2 subunit gene cluster on chromosome 5. Epilepsy Res 23: 235-244

Sander T, Hildmann T, Wienker, TF, Ramel C, Beck-Mannagetta G, Bianchi A, Sailer U, Berek K, Bauer G, Neitzel H, Schmitz B, Durner M, Johnson KJ, Janz D (1996) Common subtypes of idiopathic generalized epilepsies: lack of linkage to D20S19 close to candidate loci (EBN1, EEGV1) on chromosome 20. Am J Med Genet 67: 31-39

Shimron-Abarbanell D, Harms H, Erdmann J, Albus M, Maier W, Rietschel M, Körner J, Weigelt B, Franzek E, Sander T, Propping P, Nöthen MM (1996) Systematic screening for mutations in the human serotonin 1F receptor gene in patients with bipolar affective disorder and schizophrenia. Am J Med Genet 67: 225-228

1995

Sander T, Harms H, Podschus J, Finckh U, Nickel B, Rolfs A, Rommelspacher H, Schmidt LG (1995) Dopamine D1-, D2-, and D3 receptor genes in alcohol dependence. Psychiatr Genet 5: 177-181

Sander T, Hildmann T, Janz D, Wienker TF, Neitzel H, Bianchi A, Bauer G, Sailer U, Berek K, Schmitz B, Beck-Mannagetta G (1995) The phenotypic spectrum related to the human epilepsy susceptibility gene ?EJM1?. Ann Neurol 38: 210-217

Sander T, Janz D, Ramel C, Ross CA, Paschen W, Hildmann T, Wienker TF, Bianchi A, Bauer G, Sailer U, Berek K, Neitzel H, Volz A, Ziegler A, Schmitz B, Beck-Mannagetta G, (1995): Refinement of map position of the human GluR6 kainate receptor gene (GRIK2) and lack of association and linkage with idiopathic generalized epilepsy. Neurology 45: 1713-1720

1994

Sander T, Schmidt LG (1994): Molecular biological perspectives in treating neuropsychiatric disorders with dopaminergic drugs. Pharmacopsychiatry 27 (Suppl): 11-14

1992

Janz D, Beck-Mannagetta G, Sander T (1992): Do idiopathic generalized epilepsies share a common susceptibility gene? Neurology 42 (Suppl 5): 48-55

Johnson KJ, Sander T, Hicks AA, van Marle A, Janz D, Mullan MJ, Riley BP, Darlison MG (1992): Confirmation of the localization of the human GABAA receptor ?1-subunit gene (GABRA1) to distal 5q by linkage analysis. Genomics 14: 745-748

Lindhout D, Sander T, Halley DJJ, Kasteleijn-Nolst Trinite DGA (1992): In search for genes predisposing to epilepsy: motives and methods. Acta Neurol Scand 86 (Suppl 140): 51-58

Sander T, Rolfs A, Rommelspacher H, Schmidt LG (1992): Neuere Ergebnisse zur Genetik des Alkoholismus - eine Übersicht. Sucht 38: 270-274

Schwabe HR, Hermann R, Mathew M, Gräf KJ, Sander T, Cordes M, Nagel R, Weißbach L, Huhn D (1992): Langfristige Toxizität der Polychemotherapie bei kurativ behandeltem Hodenkarzinom. Dtsch med Wschr 117: 121-126

Walsh C, Hicks AA, Sham P, Castle D, Hunt N, Clements A, Sander T, Murray R, Darlison MG, Gill M (1992): GABAA receptor subunit genes as candidate genes for bipolar affective disorders - an association analysis. Psychiatr Genet 2: 239-247

1991 and later

Beimling P, Benter T, Sander T, Mölling K (1985): Isolation and characterization of the human cellular myc gene product. Biochemistry 24: 6349-6355

Durner M, Sander T, Greenberg D, Johnson K, Beck-Mannagetta G, Janz D (1991): Localization of idiopathic generalized epilepsy on chromosome 6p in families of juvenile myoclonic epilepsy patients. Neurology 41: 1651-1655

Mölling K, Heimann B, Beimling P, Rapp U, Sander T (1984): Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins. Nature 312: 558-561

Mölling K, Sander T, Lorenz U, Beimling P, Heimann B, Bading H (1986): Interaction of the oncogene proteine myc with specific DNA fragments: J Cancer Res Clin Oncol 112: 97-99

Skotzek B, Sander T, Zimmermann J, Kölmel HJ (1988): Oligoclonal bands in serum and CSF of patients with HIV infection. J Neuroimmunol 20: 151-152